With all his heart and soul
Figuratively: with all his might. With his entire being (nimim means thread or string).
(“The parochet is one cubit, and seventy-two threads are woven, and on each and every thread twenty-four strands” – Shekalim 8:5; and: “My father-in-law – your elder, of blessed memory – was one of the greatest Chassidim of the Gaon of Shinova, and he was attached to him with all the threads of his heart and soul” – She’elot uTeshuvot Minchat Yitzchak, Part 10, §19)
Translation
Expression (Hebrew)
בְּכָל נִימֵי נַפְשׁוֹ, בְּכָל נִים וָנִים
Definition (Hebrew)
בְּהַשְׁאָלָה: בְּכָל מְאוֹדוֹ. בְּכָל יֵשׁוּתוֹ (נִים מַשְׁמָע חוּט אוֹ מֵיתָר).
("פָּרֹכֶת עָבְיָהּ טֶפַח וְעַל שִׁבְעִים וּשְׁנַיִם נִימִין נֶאֱרֶגֶת וְעַל כָּל נִימָא וְנִימָא עֶשְׂרִים וְאַרְבָּעָה חוּטִין"-שְׁקָלִים ח ה, וְכֵן: "חוֹתְנֵי- זְקֵנְךָ זצ"ל- הָיָה מִגְּדוֹלֵי חֲסִידֵי הגה"ק מִשֶּׁינָאוָא, וְהָיָה דָּבוּק בּוֹ בְּכָל נִימֵי לְבָבוֹ וְנַפְשׁוֹ"- שׁוּ"ת מִנְחַת יִצְחָק חֵלֶק י סִימָן יט)