So what?/ What of it?

And what is unique about the word? What does this mean?

("What is it that she has tested her strength, in order to charge her husband with the same guilt? He said to him: She will not test. And she will test, and what is the matter with you? Thus - his heart is pierced and he is separated" - Nida 12:1, and so: "Say to them: Leave me alone, for I have a wife and sons, they said to him and what is the matter with you, they stood up and gave him a wife for his money" - Otzar Hamidrashim (Eisenstein) Deeds, 340, and so on: "And if a man says... - What is the matter with you? If the one who is standing there is like today, there is no white except for the sky..." - Harambam/ Letter of Repentance to Rabbi Obadiah the Emigrant, 344, and so on: "And if there are seventy-five thousand, what is the matter with you? And I am a little boy?" - Shalom Aleichem/ Seventy-five Thousand, 20, And so: "In truth, there is no such thing as a complete Shulchan and a Shulchan lacking in anything but what is in you. The emptiness of emptiness" - H. Hazaz/ Shlulit Genuza, 122, and so: "Such a question would have been dismissed by Ezekiel with a shrug of the shoulder... He knows that Zara cannot be dismissed with anything in you" - Chayim Sabato/ Ka'afafei Shahar, 130)

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